According to TMZ, the 500 square foot, 4-bedroom pad overlooking the Malibu beach west of Los Angeles was engulfed in flames from the Woolsey Fire.
Jenner has owned the home since 2015 and it has been featured multiple times on her reality series.
Meanwhile Lady Gaga's mansion nearby in Malibu was seen surrounded by a blanket of thick smoke as the blaze overtook the beachside city before moving along toward Oxnard.
So far, over 150,000 residents in Southern California have been ordered to evacuate as the Hill and Woolsey Fires move westward toward the Pacific Ocean.
At around 7am local time Friday, officials issued a mandatory evacuation order for the entire city of Malibu as the fire was declared an 'imminent threat'.